Research Areas- Clinical Research

Critical care

We lead international consortia on: critical care of “the sick child” including trials of blood transfusion and fluid resuscitation, oxygen therapy and treatment of severe malaria

Malnutrition

management of malnutrition including supportive care, nutritional rehabilitation and clinical/omic and pathophysiological pathway characterization; this work

Sickle cell

Treatment for sickle cell disease (now 1% of children in East Africa and a growing clinical burden) including trials of hydroxyurea and prophylactic antimalarials;

Antibiotic case management

The work involves trials of antibiotic stewardship.

Mental health

problems in LMIC settings are common in childhood, adolescence and adulthood and a major challenge to “the developing child”.