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RSV

Dorothy Koech

Dorothy-Koech.JPG
Email: 
dkoechatkilifi [dot] kemri-wellcome [dot] org
Group: 
Epidemiological and Demographic Surveillance System (EPI-DSS)

Dorothy is conducting research on the quantification of RSV re-infection in the community - transmission in the school setting.

Timothy Kinyanjui

Timothy-kinyanjui.JPG
Email: 
tkinyanjuiatkilifi [dot] kemri-wellcome [dot] org
Group: 
Epidemiological and Demographic Surveillance System (EPI-DSS)

Timothy is a PhD student working on mathematical modelling of respiratory syncytial virus (RSV) transmission dynamics and the impact of different vaccination strategies for its control.

Charles Sande

Charles-Sande.JPG
Email: 
csandeatkilifi [dot] kemri-wellcome [dot] org
Group: 
Epidemiological and Demographic Surveillance System (EPI-DSS)

Repiratory Syncytial Virus (RSV)

Principal Investigator(s): 
D James Nokes

A main focus of our current research is the transmission dynamics of respiratory syncytial virus, the major viral cause of infant and childhood severe pneumonia worldwide. RSV, as it is known, exhibits considerable genetic diversity (Groups A and B and within each a set of variants) which is apparently under immune selection. Occurrence of the virus is structured at the population level exhibiting sequential dominance of these variants; presumably resulting from (localised) strain specific herd immunity that provides competitive fitness to the least prevalent strains.

Transmission dynamics of respiratory viruses

Principal Investigator(s): 
D James Nokes

• Household transmission of respiratory viruses: who acquires infection from whom (Patrick Munywoki - PhD student)

• Mathematical modelling of respiratory syncytial virus (RSV) transmission dynamics and the impact of different vaccination strategies for its control (Timothy Kinyanjui, PhD Student)

• Quantifying RSV re-infection in the community - transmission in the school setting (Dorothy Koech)

• Characterising contact patterns relevant to respiratory virus transmission (Moses Kiti)

• Oral-fluid sampling for the determination of RSV infection and immunity

 

Viral genetic and antigenic variation: infection, immunity, control

Principal Investigator(s): 
D James Nokes
Other Investigator(s): 
Charles Sande


• The effects of strain variation on respiratory syncytial virus infection and Immunity (Charles Sande, PhD Student)

• RSV evolution and molecular epidemiology (Charles Nyaigoti, WT Masters Fellow)

• Genetic diversity of group A rotavirus strains in severe diarrhoeal admissions

More information:

 

D James Nokes

james-nokes.jpg
Email: 
jnokesatkilifi [dot] kemri-wellcome [dot] org
Group: 
Epidemiological and Demographic Surveillance System (EPI-DSS)

Research area
Epidemiology and control of viral pathogens

Emelda Aluoch Okiro

Emelda2.JPG
Email: 
eokiroatnairobi [dot] kemri-wellcome [dot] org
Group: 
Malaria Public Health and Epidemiology

Emelda graduated with a BSc in Chemistry and Biochemistry from Egerton University, Kenya in 2001 and joined KEMRI-Wellcome Trust-Kilifi Unit the same year as a research assistant involved in a larg