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respiratory virus

Moses Kiti

Moses-Kiti.JPG
Email: 
mkitiatkilifi [dot] kemri-wellcome [dot] org
Group: 
Epidemiological and Demographic Surveillance System (EPI-DSS)

Moses is doing research to characterise contact patterns relevant to respiratory virus transmission.

Dorothy Koech

Dorothy-Koech.JPG
Email: 
dkoechatkilifi [dot] kemri-wellcome [dot] org
Group: 
Epidemiological and Demographic Surveillance System (EPI-DSS)

Dorothy is conducting research on the quantification of RSV re-infection in the community - transmission in the school setting.

Charles Sande

Charles-Sande.JPG
Email: 
csandeatkilifi [dot] kemri-wellcome [dot] org
Group: 
Epidemiological and Demographic Surveillance System (EPI-DSS)

Repiratory Syncytial Virus (RSV)

Principal Investigator(s): 
D James Nokes

A main focus of our current research is the transmission dynamics of respiratory syncytial virus, the major viral cause of infant and childhood severe pneumonia worldwide. RSV, as it is known, exhibits considerable genetic diversity (Groups A and B and within each a set of variants) which is apparently under immune selection. Occurrence of the virus is structured at the population level exhibiting sequential dominance of these variants; presumably resulting from (localised) strain specific herd immunity that provides competitive fitness to the least prevalent strains.

Transmission dynamics of respiratory viruses

Principal Investigator(s): 
D James Nokes

• Household transmission of respiratory viruses: who acquires infection from whom (Patrick Munywoki - PhD student)

• Mathematical modelling of respiratory syncytial virus (RSV) transmission dynamics and the impact of different vaccination strategies for its control (Timothy Kinyanjui, PhD Student)

• Quantifying RSV re-infection in the community - transmission in the school setting (Dorothy Koech)

• Characterising contact patterns relevant to respiratory virus transmission (Moses Kiti)

• Oral-fluid sampling for the determination of RSV infection and immunity

 

Viral genetic and antigenic variation: infection, immunity, control

Principal Investigator(s): 
D James Nokes
Other Investigator(s): 
Charles Sande


• The effects of strain variation on respiratory syncytial virus infection and Immunity (Charles Sande, PhD Student)

• RSV evolution and molecular epidemiology (Charles Nyaigoti, WT Masters Fellow)

• Genetic diversity of group A rotavirus strains in severe diarrhoeal admissions

More information:

 

D James Nokes

Prof James Nokes.jpg
Email: 
jnokesatkilifi [dot] kemri-wellcome [dot] org

Research area
Epidemiology and control of viral pathogens