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children

Reactogenicity and immunogenicity of 10-valent pneumococcal conjugate vaccine in children

Full Title: 
Reactogenicity and immunogenicity of 10-valent pneumococcal conjugate vaccine in children aged 12-59 months
Principal Investigator(s): 
Laura L Hammitt

No description available.

Aetiology of pneumonia amongst hospitalized children in Kilifi

Principal Investigator(s): 
Laura L Hammitt

No description available.

Laura L Hammitt

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Email: 
lhammittatkilifi [dot] kemri-wellcome [dot] org
Group: 
Epidemiological and Demographic Surveillance System (EPI-DSS)

Surveillance of the burden and types of childhood diseases

Full Title: 
Surveillance of the burden and types of childhood diseases presenting to hospitals on the Kenyan coast
Principal Investigator(s): 
Jay Berkley

No description available.

Anthropometry and nutritional epidemiology in infancy

Principal Investigator(s): 
Jay Berkley

No description available.

Outpatient strategy of Ready to Use Supplementary Food (RUSF) for malnourished children

Full Title: 
A randomized trial of an outpatient strategy of Ready to Use Supplementary Food (RUSF) among moderately malnourished children following acute infection.
Principal Investigator(s): 
Jay Berkley

Acute infection is a key point of vulnerability where children's growth may falter, leading to increased susceptibility to further infection and death. RUSF is a pre-cooked, lipid-rich paste that includes essential protein, energy, fatty acids and micronutrients. It is produced in Nairobi in collaboration with Valid Nutrition and is inexpensive. The primary aims are to determine effectiveness on growth, infectious morbidity, inflammatory markers and immune activation of a short-term home-based supplementation strategy.

Daily cotrimoxazole prophylaxis following nutritional rehabilitation among children

Full Title: 
A randomized trial of daily cotrimoxazole prophylaxis following nutritional rehabilitation among children with severe malnutrition.
Principal Investigator(s): 
Jay Berkley

This project aims to test the hypothesis that mortality among Kenyan children with severe malnutrition following initial stabilisation is due to ongoing vulnerability to infectious disease, and that cotrimoxazole prophylaxis will reduce mortality. The primary endpoint is death. Secondary endpoints include the effects on growth, hospital admission, markers of inflammation, immune activation and immune function. We are also examining antibiotic resistance and changes in microbiota with prophylaxis.

Jay Berkley

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Email: 
jberkleyatkilifi [dot] kemri-wellcome [dot] org
Group: 
Clinical Group

Jay Berkley has a broad research interest in childhood infection in sub-Saharan Africa.

Fluid Expansion As Supportive Therapy (FEAST)

Principal Investigator(s): 
Kathryn Maitland

More information is available on the FEAST website.

Kathryn Maitland

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Email: 
kmaitlandatkilfi [dot] kemri-wellcome [dot] org
Group: 
Clinical Group

Kathryn Maitland specialises in paediatric infectious disease, critical care and international child health.