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neuroscience

Caroline Kathomi Mbuba

Caroline Kathomi Mbuba
Email: 
ckathomiatkilifi [dot] kemri-wellcome [dot] org
Group: 
Clinical Group

Epilepsy is the most common chronic neurological disorder, affecting approximately 50 million people worldwide, of whom 40 million are estimated to live in resource poor countries (RPC).

Haemodynamics in children with acute non-traumatic coma

Principal Investigator(s): 
Charles Newton
Other Investigator(s): 
Samson Awili Gwer

Cerebral malaria, meningitis and encephalitis are the most common causes of acute encephalopathies in children in sub-Saharan Africa. All are associated with seizures and may be complicated by shock and intracranial hypertension. These features are associated with prolonged coma, increased mortality and both short and long-term cognitive and neurological deficits. Children with multiple risk factors have even poorer outcomes.


Seizures may be completely unapparent clinically. Clinical signs of intracranial hypertension are a late feature and intracranial pressure monitoring is an invasive procedure unavailable in most health units in sub-Saharan Africa.

Samson Awili Gwer

sam-gwer.jpg
Email: 
sgweratkilifi [dot] kemri-wellcome [dot] org
Group: 
Clinical Group

Charles Newton

Email: 
cnewtonatkilifi [dot] kemri-wellcome [dot] org
Group: 
Clinical Group

No information available.

Neuroscience

Using electrodes to record electrical activity of the brain for diagnosis of epilepsyUsing electrodes to record electrical activity of the brain for diagnosis of epilepsyThe Neuroscience programme in Kilifi, Kenya aims to investigate the causes, the consequences and burden of neurological conditions in a rural tropical area, mainly affecting children. Children with neurological conditions are assessed, either on admission to hospital, after discharge from hospital or in epidemiological surveys in the community.