mapping

From the global MAP-IBD data archive, gaps in our knowledge of the distribution of malaria related IBDs have become apparent. The MPHEG's engagement in national sample surveys of infection in Kenya and regionally will open opportunities to increase the standardized description of the spatial distribution of human malaria protective gene frequencies (HbS, Glucose-6-phosphate dehydrogenase deficiency, thalassemias and Duffy coat negativity). This will enable us to better articulate HbS homozygote disease burdens, provide an informed public health decision framework for novel deployment of new pro-oxidant drugs that have haemolytic adverse effects in G6PD deficient populations, examine hypotheses of FY*O homozygote prevalence and the likelihood of P.

Kenya provides a unique set of opportunities to apply the principles of high-spatial resolution geo-statistical modelling with its rich prospectively collected national data on parasite prevalence, intervention coverage and associated covariates that relate to access to interventions and malaria risk. This work has already formed the basis of recent strategic planning for malaria control in Kenya and will be used to quantify the population-attributable infection risk reduction associated with scaled, spatially quantified intervention coverage to predict changing morbidity and mortality impact using appropriate epidemiological and burden of disease models for Kenya through to 2016.