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HIV

Francis Ndungu

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Email: 
fndunguatkilifi [dot] kemri-wellcome [dot] org
Group: 
Molecular Parasitology and Immunology

Immunity to malaria is slow to develop, is non-sterilising and wanes rapidly when immune adults migrate to non-endemic regions, suggesting that specific problems exist in the establishment and main

Eunice W Nduati

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Email: 
enduatiatkilifi [dot] kemri-wellcome [dot] org
Group: 
Molecular Parasitology and Immunology

My initial work involved the search for potential inhibitors of the Plasmodium folate pathway and monitoring of drug resistance development to anti-folate anti-malarial drugs.

Effect of HIV infection on malaria specific antibodies

Full Title: 
The effect of HIV infection on the quantities and qualities of malaria specific antibodies

No description available.

Pre-Exposure Prophylaxis (PrEP) Phase I-II Trial for MSM intermittent vs. daily regimens

Principal Investigator(s): 
Eduard Sanders

Pre-Exposure Prophylaxis (PrEP) Phase I-II Trial with mostly men who have sex with men (MSM) in Mtwapa, Kenya, as part of a multi-centre placebo-controlled study (Nairobi, and Entebbe) offering intermittent vs. daily regimens supported by IAVI.

Epidemiology of HIV and acute HIV infections in vulnerable populations

Principal Investigator(s): 
Eduard Sanders

No description available.

Eduard Sanders

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Email: 
esandersatkilifi [dot] kemri-wellcome [dot] org
Group: 
International AIDS Vaccine Initiative

Dr. Sanders is a public health physician and epidemiologist affiliated with Oxford University and supported by the International AIDS Vaccine Initiative (IAVI).

Phenotype and function of B cells in children infected with the human immunodeficiency virus (HIV)

Principal Investigator(s): 
Britta C Urban
Principal Investigator(s): 
Eunice Wambui Nduati

Hardly anything is known about the development of antigen-specific memory B cell responses to pathogens in children who are subject to profound dysregulation of the B-cell compartment due to infection with HIV. Infants and children are still in the process to acquire immunity to a wide variety of common pathogens including Plasmodium falciparum in malaria endemic areas. The proposed study will determine to which degree children infected with HIV maintain specific memory B cells responses to common childhood pathogens and vaccines before and after co-trimoxazole prophylaxis compared to HIV-uninfected children. In addition, we will establish whether co-trimoxazole prophylaxis has a beneficial effect on antigen-specific B-cell memory responses in HIV-infected children.

Susan M Graham

Email: 
grahamsmatu [dot] washington [dot] edu
Group: 
International AIDS Vaccine Initiative

Current Projects

Balancing nutritional risks and HIV prevention among HIV-exposed

Principal Investigator(s): 
Jay Berkley

No description available.